| Popis: |
Since 1962, when Jamaica experienced its first and only outbreak of eastern equine encephalomyelitis (EEE), surveillance for the causative virus has been in progress. Wild birds, rodents, mosquitoes, sandflies and sentinels (domestic chickens, guinea pigs, mice and hamsters) have been constantly examined for EEE virus and serological conversion. In essence, only negative results have been obtained. Since June 1976, domestic chickens have been investigated as a possible reservoir and several have been found to have haemagglutinating antibodies, with titres ranging from 1:10 to 1:160. These titres fell rapidly, eg, from 1:160 to 1:10 within 60 days. These results incriminate the domestic fowl as a major reservoir for the virus, and suggest that the life of immunoglobulins against EEE is short in birds. Thus, the large number of negative serological tests found in previous investigations might be misleading since positive sera might have been missed between intervals of capture and recapture of the birds. The results indicate that investigators could usefully modify their procedure by bleeding wild birds as early as one to two weeks after initial capture. The importance and duration of the dominant avian anti-EEE virus immunoglobulins should be investigated. |
