Synthesis of a C-Terminal Fluorescein-Labeled 36-mer Peptide
Autor: | Joel Burton Erickson, Catherine J. Mader, Dennis M. Lambert, Reagan J. Greene, J. William Lackey, Ralph A. Picking, Jonathan M. White |
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Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Peptides: The Wave of the Future ISBN: 9789401039055 |
Popis: | Biomedical researchers routinely incorporate fluorescently labeled peptides into assays to enhance detection sensitivity and/or to study receptor binding mechanisms associated with cellular physiology. While there are many methods available that allow a researcher to fluorescently label a peptide at the N-terminus, or on a lysine residue, there are no strategies for C-terminal labeling with fluorescein derivatives that utilize the carboxylic acid of amino acids [1,2]. |
Databáze: | OpenAIRE |
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