| Popis: |
This study was undertaken to determine whether patients who have a history of breast cancer and who may experience vaginal dryness, vaginal irritation, or dyspareunia will benefit from application of a nonhormonal polycarbophil moisturizing gel. The study design was a single-center, open label, prospective study in women with a history of breast cancer. Twenty-five women who were being treated or who had been treated for breast cancer at the clinic were enrolled from November 1990 through March 1992. Patients were instructed to insert the contents of a prefilled applicator (2.5 g) of Replens (Columbia Laboratories, Miami, FL), a polycarbophil vaginal moisturizing gel, into the vagina three times per week at night for 3 months. Patients were given the option of using an additional application of polycarbophil gel before intercourse, if desired. The main outcome measures were vaginal health assessment index, including the dryness index and measures of vaginal pH, patient acceptance, and the inciden... |
