Uterine artery embolization for symptomatic uterine myomas using gelfoam pledgets alone vs. embospheres plus gelfoam pledgets: a randomized comparison
| Autor: | George A. Vilos, Greg Garvin, Jackie Hollett-Caines, Basim Abu-Rafea, Roman Kozak, A. Oraif, Angelos G. Vilos |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
030219 obstetrics & reproductive medicine medicine.diagnostic_test Uterine fibroids business.industry medicine.medical_treatment Obstetrics and Gynecology Interventional radiology medicine.disease Embospheres 030218 nuclear medicine & medical imaging Surgery 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Uterine artery embolization Blood loss Tolerability medicine Local anesthesia business Artery |
| Zdroj: | Gynecological Surgery. 13:409-414 |
| ISSN: | 1613-2084 1613-2076 |
| Popis: | The aim of the study is to evaluate the feasibility, tolerability, and clinical outcomes of uterine artery embolization (UAE) using gelfoam (G) alone versus embospheres + gelfoam (E + G) in women with symptomatic uterine fibroids. Prospective, patient blinded, randomized controlled pilot study (Level-I). University Affiliated Teaching Hospital. Fifty-nine women with symptomatic uterine fibroids; G (n = 31) vs. E + G (n = 28). Fluoroscopy-guided trans-femoral artery UAE was performed under intravenous sedation, local anesthesia, and overnight patient-controlled analgesia (PCA) pump using either gelfoam pledgets alone or gelfoam plus embospheres (500–700 μm). Baseline, 3, 6, and 12 month dominant fibroid and total uterine volume as well as menstrual blood loss and satisfaction scores were compared between the groups. The mean and standard deviation (SD) of uterine volume (cm3) for G vs G + E at baseline and at 3, 6, and 12 months were 801 (538) vs.565 (370), 535 (226) vs. 426 (322), 485 (401) vs. 401 (249), and 467 (438) vs. 343 (227), while the mean (SD) of the dominant fibroid volume (cm3) during the same time periods were 268 (291) vs. 227 (213), 190 (290) vs. 137 (168), 132 (168) vs. 93 (101), and 118 (169) vs. 81 (99), respectively, with no statistical difference (NS) between the two groups at any interval. The corresponding mean (SD) Ruta scores assessing uterine blood loss at the same time periods were 19.2 (6.8) vs. 21.6 (6.1, NS), 11.5 (7.2) vs. 8.1 (5.2, NS), 13.2 (8.3) vs. 6.4 (4.0, p |
| Databáze: | OpenAIRE |
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