Crystallization for the Downstream Processing of Proteins
Autor: | Dirk Havekost, H.‐J. Henzler, Sebastian Schmidt, Jörg Kauling, Klaus Kaiser |
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Rok vydání: | 2005 |
Předmět: | |
Zdroj: | Engineering in Life Sciences. 5:273-276 |
ISSN: | 1618-2863 1618-0240 |
DOI: | 10.1002/elsc.200500116 |
Popis: | Protein crystallization offers great potential in downstream processing of pharmaceutical protein active ingredients. The advantages, which are well known and widely utilized in low-molecular weight crystallization, can also be expected to be found to some extent in protein crystallization. However, there is still a marked need for improvement in two main areas of protein processing, namely, in crystallization from impure solutions and scale-up. |
Databáze: | OpenAIRE |
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