Gold and Palladium Mediated Bimetallic Catalysis: Mechanistic Investigation through the Isolation of the Organogold(I) Intermediates

Autor:	Christian V. Stevens, Arno Verlee, Thomas S. A. Heugebaert, Tom van der Meer, Pavel Kerchev, Frank Van Breusegem, Kristof Van Hecke
Rok vydání:	2019
Předmět:	010405 organic chemistry Chemistry chemistry.chemical_element General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Redox Catalysis Coupling reaction 0104 chemical sciences Transmetalation Cascade reaction Reactivity (chemistry) Bimetallic strip Palladium
Zdroj:	ACS Catalysis. 9:7862-7869
ISSN:	2155-5435
DOI:	10.1021/acscatal.9b02275
Popis:	Au–Pd based catalytic systems are a unique couple due to the carbophilic Lewis acidity of Au and the redox properties of Pd. To gain more insight into this bimetallic couple, a synthetic and mechanistic investigation was conducted. As key substrates, ynamides (N-alkynyl allyloxycarbamates and N-alkynyl ethyloxycarbamates) were used. Essential for the mechanistic part was the isolation of the organogold(I) intermediate to validate the proposed mechanism. In total, 18 polysubstituted oxazolones and 12 organogold(I) complexes were synthesized.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::98617e22eba8a1191a1856015d31094f https://doi.org/10.1021/acscatal.9b02275 Zobrazit plný text záznamu