Zucker obese rats are sensitive to weight-reducing effect and insensitive to orexigenic effect by cold exposure
| Autor: | Seiki Hori, Tohru Ishigaki, Kazuko Hori, Hitomi Takeda, Katsuhiro Koyama, Mitsuharu Kaya, Junzo Tsujita |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
Food intake Physiology business.industry Cold exposure nutritional and metabolic diseases Biochemistry Acclimatization Rate of increase Endocrinology medicine.anatomical_structure Orexigenic Internal medicine Brown adipose tissue medicine General Agricultural and Biological Sciences business Developmental Biology medicine.drug |
| Zdroj: | Journal of Thermal Biology. 26:479-483 |
| ISSN: | 0306-4565 |
| Popis: | Male Wistar and Zucker (lean and obese) rats at 7 weeks of age were divided into three groups: warm-acclimated (25°C for 11 weeks), cold-acclimated (10°C for 11 weeks), and deacclimated (10°C for 9 weeks and 25°C for 2 weeks) groups. The rate of increase in body mass (BM) was lower in obese rats as compared to lean rats. Cold-acclimated Wistar and Zucker lean rats exhibited greater food intake, compared to warm-acclimated rats. Food intake did not increase in obese rats exposed to cold. Obese rats are sensitive to weight-reducing effect and insensitive to the orexigenic effect by cold exposure. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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