Adaptive Immunity Dysregulation in Acute Coronary Syndromes
| Autor: | Cornelia M. Weyand, Davide Flego, Filippo Crea, Giovanna Liuzzo |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Acute coronary syndrome business.industry 030204 cardiovascular system & hematology Acquired immune system medicine.disease Sudden cardiac death Pathogenesis 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Heart failure Pandemic Immunology Medicine Cardiology and Cardiovascular Medicine business Intensive care medicine |
| Zdroj: | Journal of the American College of Cardiology. 68:2107-2117 |
| ISSN: | 0735-1097 |
| Popis: | Although the early outcome of acute coronary syndrome (ACS) has considerably improved in the last decade, cardiovascular diseases still represent the main cause of morbidity and mortality worldwide. This is mainly because recurrence of ACS eventually leads to the pandemics of heart failure and sudden cardiac death, thus calling for a reappraisal of the mechanisms responsible for coronary instability. This review discusses recent advances in our understanding of how adaptive immunity contributes to the pathogenesis of ACS and the clinical implications that arise from these new pathogenic concepts. |
| Databáze: | OpenAIRE |
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