James Malone-Lee responds to the media flurry over safety of anticholinergic drugs in elderly people

Autor:	James Malone-Lee
Rok vydání:	2011
Předmět:	Gerontology Geriatrics medicine.medical_specialty Scrutiny business.industry General Engineering General Medicine Cholinergic Antagonists General Earth and Planetary Sciences Elderly people Medicine business Drug toxicity Anticholinergic Drugs General Environmental Science Mass media
Zdroj:	BMJ. 343:d4740-d4740
ISSN:	1468-5833 0959-8138
DOI:	10.1136/bmj.d4740
Popis:	The intemperate hubbub over anticholinergic safety in elderly people, championed by the BBC on the morning of 24 June 2011, merits sober reflection.1 The focus was a paper by Fox and colleagues that was unavailable until 4 pm,2 when placed on the website of the Journal of the American Geriatrics Society . By then the media squall had dissipated. Recent UK history should deter such ill advised announcement of data through television, before it is published for peer scrutiny. The article in question was a post hoc analysis of epidemiological data collected from older adults enrolled in the Medical Research Council Cognitive Function and Ageing Study. Participants were assessed using the mini-mental state examination (MMSE) in 1991 and 1993. The paper was published as an early online brief report, short on detail. Anticholinergic exposure was measured crudely using a ranked …
Databáze:	OpenAIRE
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