Stereoselective Total Synthesis of Stagonolide E

Autor:	Katragadda Suresh Babu, Udugu Ramulu, Seema Aravind, Singanaboina Rajaram
Rok vydání:	2015
Předmět:	Inorganic Chemistry Stagonolide E Chemistry Stereochemistry Organic Chemistry Drug Discovery Total synthesis Organic chemistry Stereoselectivity Physical and Theoretical Chemistry Biochemistry Catalysis
Zdroj:	Helvetica Chimica Acta. 98:650-656
ISSN:	0018-019X
DOI:	10.1002/hlca.201400265
Popis:	An efficient and highly stereoselective synthesis of stagonolide E (1) starting from the readily available hexane-1,6-diol (8) was accomplished, employing MacMillan α-hydroxylation, Horner WadsworthEmmons olefination, (Z)-selective StillGennari olefination, and Yamaguchi lactonization as key steps.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::982751725fb8896036a61b834da4f2a0 https://doi.org/10.1002/hlca.201400265 Zobrazit plný text záznamu Plný text ve formátu PDF