4'-(2-Butyl-4-chloro-5-formylimidazol-1-ylmethyl)biphenyl-2-carbonitrile

Autor: Padmarajaiah Nagaraja, Rajenahally S. Narasegowda, Hemmige S. Yathirajan, Basavegowda Nagaraj, Michael Bolte
Rok vydání: 2005
Předmět:
Zdroj: Acta Crystallographica Section E Structure Reports Online. 61:o1193-o1195
ISSN: 1600-5368
DOI: 10.1107/s1600536805009487
Popis: The title compound, C22H20ClN3O, ( I), is used as an intermediate for the synthesis of the antihypertensive drug losartan. Bond lengths and angles are unexceptional. The crystal packing is stabilized by one C - H center dot center dot center dot O and one C-H center dot center dot center dot N contact. It is noteworthy that ( I) is isomorphous with a closely related compound which differs in having a but-2-enyl chain instead of a butyl chain on the imidazole ring.
Databáze: OpenAIRE