In-Vitro Antibacterial, Antioxidant and Cytotoxic Potential of Silver Nanoparticles Synthesized Using Novel Eucalyptus tereticornis Leaves Extract
| Autor: | M. S. Kiran, Virupaxappa S. Betageri, M. S. Latha, S. P. Vinay, C. R. Rajith Kumar |
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| Rok vydání: | 2020 |
| Předmět: |
Antioxidant
Polymers and Plastics biology DPPH medicine.medical_treatment 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology biology.organism_classification medicine.disease_cause 01 natural sciences Silver nanoparticle 0104 chemical sciences Eucalyptus tereticornis chemistry.chemical_compound chemistry Staphylococcus aureus Materials Chemistry medicine 0210 nano-technology Antibacterial activity Escherichia coli IC50 Nuclear chemistry |
| Zdroj: | Journal of Inorganic and Organometallic Polymers and Materials. 30:2916-2925 |
| ISSN: | 1574-1451 1574-1443 |
| DOI: | 10.1007/s10904-020-01443-7 |
| Popis: | In present study, silver nanoparticles (AgNPs) were synthesized using Eucalyptus tereticornis leaves extract as bioreducing agent. Prepared AgNPs were characterized and confirmed using various analytical tools such as UV–Vis spectroscopy, XRD, SEM with EDS and TEM. Crystallographic studies were carried by XRD analysis. Size, morphology was studied by SEM, TEM and elemental composition confirmed by EDS respectively. AgNPs showed significant antibacterial activity against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus bacterial strains. AgNPs also exhibited promising 1,1-Diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with IC50 59.0 μg/mL. Further, cytotoxic activity performed on Michigan Cancer Foundation-7 (MCF-7) cell line proved that the prepared AgNPs have potential anticancer activity having 63.257 μg/ml 50% inhibition concentration. |
| Databáze: | OpenAIRE |
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