| Autor: |
Amparo Santamaria Ortiz, Hiurma Sánchez Pérez, María Ángeles Martínez Zamora, Betina Nishishinya, Gisela Díaz-Cordovés Rego, María José Cuadrado Lozano, María Paloma Delgado Beltrán, Olga Amengual Pliego, Petra Díaz del Campo Fontecha, Clara Fuego Varela, Evelin Cecilia Cervantes Pérez, María Martín López, Claudia Pereda Testa, Lucía Silva-Fernández, Sandra Garrote Corral, Víctor Martínez Taboada, Francisco Javier López Longo, Maria Galindo Izquierdo, Rafael Cáliz, Marta Novella Navarro, Loreto Carmona Ortells |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Reumatología Clínica. 16:71-86 |
| ISSN: |
1699-258X |
| DOI: |
10.1016/j.reuma.2018.11.003 |
| Popis: |
Objective The difficulty in diagnosis and the spectrum of clinical manifestations that can determine the choice of treatment for primary antiphospholipid syndrome (APS) has fostered the development of recommendations by the Spanish Society of Rheumatology (SER), based on the best possible evidence. These recommendations can serve as a reference for rheumatologists and other specialists involved in the management of APS. Methods A panel of four rheumatologists, a gynaecologist and a haematologist with expertise in APS was created, previously selected by the SER through an open call or based on professional merits. The stages of the work were: identification of the key areas for drafting the document, analysis and synthesis of the scientific evidence (using the Scottish Intercollegiate Guidelines Network [SIGN] levels of evidence) and formulation of recommendations based on this evidence and formal assessment or reasoned judgement techniques (consensus techniques). Results 46 recommendations were drawn up, addressing five main areas: diagnosis and evaluation, measurement of primary thromboprophylaxis, treatment for APS or secondary thromboprophylaxis, treatment for obstetric APS and special situations. These recommendations also include the role of novel oral anticoagulants, the problem of recurrences or the key risk factors identified in these subjects. This document reflects the first 21, referring to the areas of: diagnosis, evaluation and treatment of primary APS. The document provides a table of recommendations and treatment algorithms. Conclusions An update of the SER recommendations on APS is presented. This document corresponds to part I, related to diagnosis, evaluation and treatment. These recommendations are considered tools for decision-making for clinicians, taking into consideration both the decision of the physician experienced in APS and the patient. A part II has also been prepared, which addresses aspects related to obstetric SAF and special situations. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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