Percutaneous Coronary Intervention in Women: In-Hospital Clinical Outcome

Autor: Ronald Dick, Ernesto Oqueli, Martin Hiscock, Leonie Baker, Aaron Carroll
Rok vydání: 2008
Předmět:
Zdroj: Heart, Lung and Circulation. 17:S55-S62
ISSN: 1443-9506
Popis: Background Differences in outcome between women and men treated with percutaneous coronary intervention (PCI) have decreased. This study was aimed at assessing the demographic, clinical, and angiographic features, procedural characteristics and in-hospital results of women undergoing PCI and comparing their results with those of a group of men undergoing PCI throughout the same period of time. Methods and Results All consecutive PCI procedures performed at Epworth Hospital from November 2004 to January 2007 were analysed. Women and men were compared according to baseline clinical, angiographic and procedural characteristics, angiographic success rates and in-hospital outcomes. A total of 1699 consecutive PCI procedures were performed; of these, 405 PCI (23.8%) were performed in women. Women were older (73.9 ± 10 years versus 66.1 ± 11.9 years, p Women had more complex lesions B2/C (78% versus 74%, p = 0.049), a higher proportion of ostial lesions (10.5% versus 5.5%, p Total unadjusted in-hospital mortality was higher in women than in men (1.97% versus 0.54%, respectively, p = 0.013). This difference in mortality was only at the expense of a higher unadjusted mortality in women presenting with ST segment elevation myocardial infarction (STEMI) than men (17.5% versus 1.87%, p = 0.002). No women with a stable coronary syndrome or non-ST-segment elevation acute coronary syndrome (NSTE-ACS) died in hospital. There were no differences in in-hospital myocardial infarction, new revascularisation or stroke between both groups. Conclusions PCI in women has good results but carries an increased unadjusted mortality than in men. This mortality difference between genders in our study, however, was solely at the expense of a higher unadjusted mortality in women than in men undergoing PCI for STEMI.
Databáze: OpenAIRE