The synthesis of phenolic cryptands–efficient acid catalysis in a molecular cavity

Autor:	Ian O. Sutherland, Alastair F. Sholl
Rok vydání:	1992
Předmět:	chemistry.chemical_classification Cryptand Salt (chemistry) Nuclear magnetic resonance spectroscopy Acid catalysis chemistry.chemical_compound chemistry Bromide Polymer chemistry Molecular Medicine Organic chemistry Benzene Acetonitrile Demethylation
Zdroj:	J. Chem. Soc., Chem. Commun.. :1252-1253
ISSN:	0022-4936
DOI:	10.1039/c39920001252
Popis:	The reaction of 1,3-bisbromomethyl-2-methoxy benzene with diaza-15-crown-5 or diaza-18-crown-6 in acetonitrile gives the phenolic cryptands 6a and 6c; it is shown that the formation of 6a involves the methoxy cryptand salt 9 which undergoes efficient demethylation by bromide anion as a result of acid catalysis within the cavity of the cryptand system.
Databáze:	OpenAIRE
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