Uncontrolled non-heartbeating donors (types I–II) with normothermic recirculation vs. heartbeating donors: Evaluation of functional results and survival

Autor: José Medina-Polo, J.B. Passas-Martínez, M. Pamplona-Casamayor, F. De La Rosa Kehrmann, N. Miranda-Utrera, Ángel Tejido-Sánchez, F. Villacampa Aubá, A. Andrés Belmonte, Alfredo Rodríguez-Antolín, José Manuel Duarte-Ojeda
Rok vydání: 2015
Předmět:
Zdroj: Actas Urológicas Españolas (English Edition). 39:429-434
ISSN: 2173-5786
Popis: Objective Non-heartbeating donors (NHBD) are an alternative to heartbeating donors (HBD). Our objective was to compare functional results and kidney survival from NHBDs and HBDs. Material and methods A retrospective study comparing the results of 236 normothermically preserved kidneys from type I and type II NHBDs with the results of 250 from HBDs that were transplanted in our center between 2005 and 2012. Homogeneity between groups was tested and we evaluated the presence of delayed graft function (DGF) associated with pretransplant variables of the donor and recipient. Results Both groups show homogeneity in pretransplant characteristics in terms of: age, HLA incompatibilities, and recipient hemodialysis time. Average follow-up time was 33 months (range 0–87) for NHBDs and 38 months (range 0–90) for HBDs. 5.5% of NHBDs showed primary non-function (PNF) vs. 4% of HBDs ( p = 0.42) and 80.9% of DGF vs. 46.8% of HBDs ( p p = 0.71) and recipients (99.1% NHBD vs. 98.6% HBD, p = 0.28). Conclusions Although the DGF percentage was greater for NHBDs, final creatinine as well as graft and recipient survival were similar for both groups. Therefore, in our experience, kidneys from NHBDs have similar results to those from HBDs and are an excellent source of organs for transplantation.
Databáze: OpenAIRE