Children with Acute Asthma: IgE Antibody Reactivities to Fungi, House Dust Mites, Cockroaches, and Other Indoor Allergens
| Autor: | Wendell N. Colberg, Gerald Reese, Samuel B. Lehrer, J.M. El-Dahr, Marjorie McCants |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Pulmonary and Respiratory Medicine
Cockroach Allergy medicine.diagnostic_test biology Radioallergosorbent test Fungi imperfecti Dust mites Immunoglobulin E biology.organism_classification medicine.disease respiratory tract diseases immune system diseases biology.animal Pediatrics Perinatology and Child Health Immunology medicine biology.protein Mite Immunology and Allergy Asthma |
| Zdroj: | Pediatric Asthma, Allergy & Immunology. 14:59-67 |
| ISSN: | 1557-7767 0883-1874 |
| Popis: | Allergens are known to be a significant cause of asthma. The aim of this study was to assess immunoglobulin E (IgE) antibody reactivity to fungi, basidiomycetes and fungi imperfecti, house dust mites, cockroaches, and other indoor allergens, in young asthmatics with acute asthma exacerbation. Forty-nine subjects (2.5 months to 14 years old, mean age 7.3 years) presenting to the emergency room with symptoms of acute asthma were tested for specific IgE antibodies to basidiomycetes, fungi imperfecti, German and American cockroach, cat, and house dust mites. Positive radioallergosorbent test (RAST) reactivity was most frequent (67.3%) and the greatest (up to 62.6%) to house dust mites. Children older than 5 years exhibited a substantial increase in mite-specific positive RAST reactivity compared to younger children. Frequency of IgE antibodies increased from 77% of subjects older than 2 years of age to 88% of subjects older than 6 years. The basis of this increase in mite reactivity after age of 5 ye... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|