Predictors of stage at presentation and outcomes of head and neck cancers in a university hospital setting
| Autor: | Mark A. Varvares, Adnan S. Hussaini, Nosayaba Osazuwa-Peters, Kara M. Christopher, Ronald J. Walker, Anit Behera |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
business.industry Proportional hazards model Head and neck cancer Odds ratio Race and health Logistic regression medicine.disease Confidence interval Surgery 03 medical and health sciences 0302 clinical medicine Otorhinolaryngology 030220 oncology & carcinogenesis Internal medicine Medicine 030212 general & internal medicine Stage (cooking) Presentation (obstetrics) business |
| Zdroj: | Head & Neck. 38:E1826-E1832 |
| ISSN: | 1043-3074 |
| Popis: | Background To increase early detection of head and neck cancers, it is important that disparities associated with access to care are addressed. Methods A total of 351 patients aged 20 to 91 years (58.72 ± 11.70 years) diagnosed with head and neck cancers at a university hospital from 1997 to 2010 were analyzed. Logistic regression assessed the association between clinical stage at presentation and predictors. Cox proportional hazards model assessed the effect of stage at presentation on survival. Results Being African American was associated with increased odds of late stage at presentation (adjusted odds ratio [OR] = 2.16; 95% confidence interval [CI] = 1.01–4.59), and those without health insurance were 10.97 times more likely to present at late stage (95% CI = 1.30–92.49). Unmarried patients were 1.6 times at an increased hazard of death (95% CI = 1.12–2.24). Conclusion Disparities, such as race and health insurance status, are important predictors of stage at presentation of patients with head and neck cancer. © 2015 Wiley Periodicals, Inc. Head Neck, 2015 |
| Databáze: | OpenAIRE |
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