Investigation of interaction of albumin molecules with diamond nanoparticles in aqueous solutions by dynamic light scattering
| Autor: | Galina P. Petrova, Elena Perevedentseva, T.-H. Su, V. V. Gibizova, Alexander V. Priezzhev, Andrei E. Lugovtsov, Y.-S. Ye, Chia-Liang Cheng, Yu S Samsonova |
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| Rok vydání: | 2012 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Range (particle radiation) Materials science Aqueous solution Hydrodynamic radius Nanoparticle Statistical and Nonlinear Physics Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials body regions Adsorption Dynamic light scattering Chemical engineering Carboxylation hemic and lymphatic diseases parasitic diseases Molecule Electrical and Electronic Engineering |
| Zdroj: | Quantum Electronics. 42:484-488 |
| ISSN: | 1468-4799 1063-7818 |
| Popis: | The method of dynamic light scattering has been used to study the interaction of albumin molecules with diamond nanoparticles in aqueous solutions. It is shown that due to adsorption of albumin on diamond nanoparticles, larger size particles are formed. We have obtained the concentration dependences of the average hydrodynamic radius of these particles. It is found that the carboxylation of the surface of diamond nanoparticles and their pre-coating by albumin leads to a decrease in the adsorption of protein molecules on the surface of nanoparticles and to a decrease in their average hydrodynamic radius. We have also shown that in the range of concentrations of diamond nanoparticles 2–10 μg mL-1, their interaction with albumin molecules at different pH has a different character. |
| Databáze: | OpenAIRE |
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