Cube-shaped Triethylene Glycol-coated Ni−Mn Ferrite Nanoparticles for use as T2 Contrast Agents in Magnetic Resonance Imaging
| Autor: | Chan Kim, Ilsu Rhee, Hyewon Chung, Hongsub Bae |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
010302 applied physics
Materials science MRI contrast agent Spinel General Physics and Astronomy Nanoparticle 02 engineering and technology Coercivity engineering.material 021001 nanoscience & nanotechnology 01 natural sciences Hydrothermal circulation chemistry.chemical_compound chemistry Coating Chemical engineering 0103 physical sciences engineering Inductively coupled plasma 0210 nano-technology Triethylene glycol |
| Zdroj: | Journal of the Korean Physical Society. 74:48-52 |
| ISSN: | 1976-8524 0374-4884 |
| DOI: | 10.3938/jkps.74.48 |
| Popis: | Nickel-manganese (Ni−Mn) ferrite nanoparticles were synthesized using the hydrothermal technique and were coated with the biocompatible material of triethylene glycol (TEG) during the synthetic process. The chemical composition of the particles was Ni0.5Mn0.5Fe2O4 based on the use of inductively coupled plasma (ICP). The shapes of the particles were cubic in the TEM images and had an average side length of 68 nm. The XRD patterns confirmed the inverse spinel structure of these particles. The FTIR spectra also showed the firm coating of the TEG on the surfaces of these particles. The saturation magnetization of the particles was observed to be 66 emu/g with a coercive force of 150 Oe. The T1 and T2 relaxivities of the hydrogen protons in the aqueous dispersion of the particles were 0.32 and 15.59 mM−1s−1, respectively. The ratio of r2/r1 was 48.72, thus indicating that the Ni0.5Mn0.5Fe2O4 nanoparticles are applicable as high-efficacy T2 contrasts agents in MRI. |
| Databáze: | OpenAIRE |
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