ULTRAVIOLET EXPOSURE AND 250H VITAMIN D IN BREAST-FED INFANTS IN BEIJING, CHINA

Autor:	Qing-mei Shui, Mona Ho, Xue-cun Chen, Why-Cheng Yen, Reginald C. Tsang, Bonny Specker, Buford Lee Nichols
Rok vydání:	1984
Předmět:	Pediatrics medicine.medical_specialty business.industry Incidence (epidemiology) Rickets medicine.disease Animal science Pediatrics Perinatology and Child Health medicine Vitamin D and neurology Fruit juice Sun exposure business Normal range
Zdroj:	Pediatric Research. 18:184A-184A
ISSN:	1530-0447 0031-3998
DOI:	10.1203/00006450-198404001-00544
Popis:	A high incidence of rickets among infants in the Peoples Republic of China has been reported, etiology unclear. The vit. D status of infants in China has not been investigated. The specific effect of sunshine (UV) exposure on D status in any infant is unstudied. We hypothesized that breast-fed infants in China have low vit. D status and UV exposure increases serum 25OH vit. D into the normal range. 54 breast-fed term infants 1 to 8 mos. without D supplements were randomly assigned into 2 grps. in a 2 mo. study, Sept. and Oct. (mos. of high UV exposure): controls with "usual" sun exposure; and experimental with 2 hr. sun/d. Infants received only human milk, rice soup, fruit juice and mashed vegetables and exposed mostly face and forearms. A 20 nurse team monitored UV exposure with diaries and a unique infant UV dosimeter. Only 100 μl blood samples were permissible in infants. Serum 25OHD was measured by protein binding assay after chromatography. (N 11 to 68 ng/ml). Mean maternal 25OHD was 22 ng/ml. Infant 25OHD correlated with mother's (r=0.48). Infant 25OHD ranged 3 to 61 ng/ml at entry with 20%
Databáze:	OpenAIRE
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