OPTIMIZATION OF EX VIVO PRESSURE MEDIATED DELIVERY OF ANTISENSE OLIGODEOXYNUCLEOTIDES TO ICAM-1 REDUCES REPERFUSION INJURY IN RAT CARDIAC ALLOGRAFTS1

Autor:	Robert S. Poston, Aric K. Park, Robert C. Robbins, Brian T. Feeley, Michael P. Ennen, Patrick W. Vriens, Hoyt Eg
Rok vydání:	2000
Předmět:	Transplantation ICAM-1 Antisense oligodeoxynucleotides Chemistry Adhesion Transfection Pharmacology medicine.disease Hyperbaric pressure Molecular biology medicine Reperfusion injury Ex vivo Intracellular
Zdroj:	Transplantation. 69:1067-1074
ISSN:	0041-1337
DOI:	10.1097/00007890-200003270-00009
Popis:	Background.Our purpose was to optimize hyperbaric pressure as a vector for ex vivo transfection of antisense oligodeoxynucleotides (AS-ODN) to intercellular adhesion molecule-1 to limit reperfusion injury (RI) in cardiac allografts.We investigated the effects of increased pressure, incubation time
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::978050c6820352daec0a16573d158a31 https://doi.org/10.1097/00007890-200003270-00009 Zobrazit plný text záznamu