Expression of c-Met in ovarian epithelial tumor
| Autor: | Il Soo Park, Bo Seop Kim, Tae Bon Koo, Yoon Soon Lee, Tae In Park |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
education.field_of_study
Pathology medicine.medical_specialty C-Met endocrine system diseases business.industry Population chemistry.chemical_compound Ovarian Epithelial Tumor chemistry Epithelial ovarian carcinoma Ovarian carcinoma Tumor stage Medicine Ovarian carcinomas Stage (cooking) business education |
| Zdroj: | Korean Journal of Gynecologic Oncology. 18:284 |
| ISSN: | 1738-6543 |
| DOI: | 10.3802/kjgo.2007.18.4.284 |
| Popis: | Objective : This study was performed to evaluate the expression of c-Met in epithelial ovarian carcinoma. Methods : Paraffin-embedded tissues from 50 epithelial ovarian adenocarcinomas were stained immunohistochemically for c-Met expression. The expression of c-Met was correlated with clinicopathologic parameters including, histologic type, tumor size, and tumor stage. Results : c-Met expression was found in 29 cases (58%) among 50 ovarian cancers. In clinicopathologic study, c-Met expression of epithelial ovarian carcinomas did not show the correlation with clinicopathologic parameters such as histologic type, tumor size and stage. Conclusion : c-Met expression might be a potential prognostic marker for patients with advanced stage epithelial ovarian cancers. However, larger population-based studies should be performed to determine the prognostic potential of c-Met expression in advanced ovarian carcinoma. |
| Databáze: | OpenAIRE |
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