| Autor: |
Achiè Aurélie Yenon, Allico Joseph Djaman, Dit Philippe Bidié Alain, Franck Mansour Adeoti, Bi Foua Jonas Vanie |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Asian Journal of Biochemistry, Genetics and Molecular Biology. :1-8 |
| ISSN: |
2582-3698 |
| DOI: |
10.9734/ajbgmb/2019/v2i130053 |
| Popis: |
Entandrophragma angolense is a plant of the family Meliaceae of African pharmacopoeia. It is used in traditional medicine as an analgesic and anti-inflammatory in cases of abdominal or hips pain. The aim of this study is to compare the effect of oral administration of aqueous extract of E. angolense and vitamin B12 on hemolytic induced anemia and inflammation in the rat. Anemia was induced by intraperitoneal administration of phenylhydrazine at the dose of 40 mg / kg / day for two days in 24 Wistar rats, followed by aqueous extract of E. angolense and vitamin B12 chosen as reference molecule administered orally to rats once a day for 28 days. A biological assessment on blood count, CRP and the study of secondary metabolites of the aqueous extract of E. angolense have been realized. The results obtained showed the existence of anemia characterized by a significant decrease (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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