Angioleiomioma renal con patrón inmunohistoquímico miogénico y melanocítico como variante del angiomiolipoma
Autor: | Candelaria García Castro, Laura González Pérez, Hugo Álvarez-Argüelles Cabrera, Jorge A. López García, Ángel Nazco Deroy, Sonia García Hernández, Isabel González Villa |
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Rok vydání: | 2020 |
Předmět: |
Pathology
medicine.medical_specialty Angiomyolipoma biology business.industry 030232 urology & nephrology Nodule (medicine) medicine.disease Pathology and Forensic Medicine Renal neoplasm 03 medical and health sciences Caldesmon 0302 clinical medicine 030220 oncology & carcinogenesis biology.protein Medicine Neoplasm Immunohistochemistry Desmin medicine.symptom business Actin |
Zdroj: | Revista Española de Patología. 53:66-70 |
ISSN: | 1699-8855 |
DOI: | 10.1016/j.patol.2018.07.002 |
Popis: | We present a case of a 67 year old male with a cortical nodular tumour of the left kidney. During a year's follow-up with ultrasound and MRI, the tumour was seen to increase in size by 16-20 mm. The nodule was surgically removed. Microscopically it was well defined and unencapsulated, with a proliferation of typical fusiform cells of smooth muscle cell appearance, clumped around well vascularized areas. Immunohistochemically, the neoplasm was positive for muscle markers (smooth muscle actin, desmin and caldesmon) and melanocyte markers (HMB-45 and Melan A). Our case would appear to be a renal neoplasm with an angioleiomyomatous pattern, but with immunohistochemical characteristics of angiomyolipoma (PEComa), however, without either a lipomatous or lipid cell component. We found no previous reports of this type of tumour in the literature. |
Databáze: | OpenAIRE |
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