Reducing radiation dermatitis during ongoing radiation therapy: an innovative film-forming wound dressing
| Autor: | Amparo Quilis, Purificación Sánchez, Jaime Martín, Juan Luis Ribes, Concepción Rodríguez |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
integumentary system Erythema business.industry medicine.medical_treatment Cancer medicine.disease Dermatology 030218 nuclear medicine & medical imaging Desquamation Radiation therapy 03 medical and health sciences 0302 clinical medicine Moist desquamation Quality of life 030220 oncology & carcinogenesis Wound dressing medicine medicine.symptom business Burning Sensation |
| Zdroj: | Journal of Radiation Oncology. 7:255-264 |
| ISSN: | 1948-7908 1948-7894 |
| DOI: | 10.1007/s13566-018-0356-5 |
| Popis: | This multicenter study focuses on the use of a film-forming wound dressing in the form of a gel that can be applied directly to the area affected by radiation dermatitis, especially after skin breakdown. The primary objective of the study was to validate the efficacy of an innovative film-forming wound dressing used as monotherapy in the treatment of radiation dermatitis in patients with RTOG score 2.5 (± 0.5) confirmed by the investigator. Fifty-four patients undergoing radiation therapy for different cancer types and developing radiation dermatitis were recruited in the study; they were treated with the film-forming wound dressing when reaching an RTOG score of 2.5 (± 0.5). The evaluation of radiation dermatitis during ongoing radiation therapy was performed using the RISRAS, which includes investigator-assessed items (erythema, dry desquamation, moist desquamation, necrosis) and patient-assessed items (pain, itch, burning sensation, affection of daily activities). The following study shows a statistically significant clinical improvement (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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