Dolor abdominal, dispepsia y gastritis en pediatría: Rol del Helicobacter pylori
| Autor: | F Alex Godoy, D Paul Harris, C Ernesto Guiraldes |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
biology business.industry Chronic gastritis Cancer MALT lymphoma Disease Helicobacter pylori medicine.disease biology.organism_classification Gastroenterology digestive system diseases Pathogenesis Internal medicine Pediatrics Perinatology and Child Health Epidemiology medicine Gastritis medicine.symptom business |
| Zdroj: | Revista chilena de pediatría. 72 |
| ISSN: | 0370-4106 |
| DOI: | 10.4067/s0370-41062001000200002 |
| Popis: | Helicobacter pylori (H. pylori) is the most common bacterial pathogen of the gastrointestinal tract in humans and also the most common cause of chronic gastritis and is aetiologically associated with duodenal and gastric ulcer, gastric adenocarcinoma and MALT lymphoma. The explosive accumulation of published reports makes it necessary to review the concepts of gastritis, recurrent abdominal pain and dyspepsia in children. Therefore the aim of this study was to update the concepts and to clarify their relationship with H. pylori and to discuss their validity in order to promote good clinical practice. Causative associations between H. pylori infection and other conditions are tenuous and speculative, these conditions include recurrent abdominal pain and non-ulcer dyspepsia. H. pylori is firmly established as a human pathogen because it fulfills each of Koch´s postulates as an infective agent causing chronic-active gastritis. Indeed H. pylori plays a critical and necessary role in the pathogenesis of chronic -active gastritis in adults. Whether H. pylori is a cause of peptic ulcer disease is less well established in children, nevertheless, the evidence for its causation is compelling. There is a strong epidemiological association between H. pylori and peptic ulceration in the absence of drug ingestion in adults. Although many people are infected, only a samll proportion will have clinical manifestations of disease. Approximately 10% of those infected will develop peptic ulcer disease during their lifetime. Infected persons have a 2-6 fold increased risk of developing cancer or MALT lymphoma compared to their uninfected counterparts. |
| Databáze: | OpenAIRE |
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