Characterization of Compounds From Extract of Leaf Cloroform Melochia umbellata (Houtt.) Stapf var. Degrabrata K. and Test Antihiperglicemic Activities
| Autor: | Hanapi Usman, Nunuk Hariani Soekamto, Imran Imran |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
Glucose tolerance test Chloroform Chromatography medicine.diagnostic_test biology Fatty acid Fractionation biology.organism_classification Glibenclamide chemistry.chemical_compound chemistry medicine Maceration (wine) Melochia umbellata lipids (amino acids peptides and proteins) medicine.drug |
| Zdroj: | Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta). 10:1 |
| ISSN: | 2655-6049 2085-014X |
| DOI: | 10.20956/ica.v10i2.6650 |
| Popis: | A research on the characterization of the chloroform extract of leaves of M. umbellata (Houtt.) stapf var. degrabrata K. and activity test as antihyperglycemic has been done. This study aimed to isolate and characterize compounds from chloroform extract and determine the optimum concentration of chloroform extract in reducing blood glucose levels. Isolation compound from chloroform extract has been done by maceration, fractionation and purification. Based on the data of IR and NMR spectroscopic, compounds isolated from this research were β-sitosterol and fatty acid compound consisting of 25 carbon atoms. The glucose tolerance test, concentration of 6% showed a decrease in glucose levels almost equivalent with drug glibenclamide as comparator. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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