| Autor: | Sophie Berland, F. Moutahir-belqasmi, Nicole Balmain, M. Lieberrher, Sandrine Borzeix, Jean Peduzzi, Christian Milet, Evelyne Lopez, M. Barthelemy |
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| Rok vydání: | 2001 |
| Předmět: |
musculoskeletal diseases
biology Biomedical Engineering Biophysics Bioengineering Osteoblast Cell cycle Matrix (biology) biology.organism_classification Cell biology Biomaterials medicine.anatomical_structure Biochemistry Pinctada maxima Bone cell medicine Alkaline phosphatase Bone regeneration Mitosis |
| Zdroj: | Journal of Materials Science: Materials in Medicine. 12:1-6 |
| ISSN: | 0957-4530 |
| DOI: | 10.1023/a:1026759431595 |
| Popis: | The nacre (mother of pearl) layer of the oyster Pinctada maxima shell can initiate bone formation by human osteoblasts in vivo and in vitro and is a new biomaterial that induces osteogenesis. This activity of nacre could be due to its water-soluble matrix. We examined the action of a water-soluble extract of nacre on the osteoblast phenotype of cells isolated from rat neonatal calvaria by measuring alkaline phosphatase (ALP) activity and by localization of the anti-apoptotic protein Bcl-2 by immunocytochemistry. ALP activity was increased 7% (p |
| Databáze: | OpenAIRE |
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