Autor: | M A Aleksandrova, I. V. Paramonova, Perova Nv, Akhmedzhanov Nm, I. N. Ozerova, Olfer'ev Am |
---|---|
Rok vydání: | 2001 |
Předmět: |
Chromatography
Chemistry Cholesterol Silica gel Phospholipid nutritional and metabolic diseases High density General Medicine General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Simvastatin medicine lipids (amino acids peptides and proteins) Composition (visual arts) In patient After treatment medicine.drug |
Zdroj: | Bulletin of Experimental Biology and Medicine. 132:763-765 |
ISSN: | 0007-4888 |
DOI: | 10.1023/a:1013034029290 |
Popis: | We studied the phospholipid composition of high-density lipoproteins in patients with hypercholesterolemia before and after treatment with simvastatin. Individual phospholipids were separated by thin-layer chromatography on glass plates coated with silica gel. It was found that apart from hypolipidemic effect, simvastatin changed the concentration and phospholipid composition of high-density lipoproteins, which improved their cholesterol-accepting and cholesterol-transporting properties. |
Databáze: | OpenAIRE |
Externí odkaz: |