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Objective To assess to prognostic value of pre-operative plasma NT-proBNP combined with creatinine in early outcomes after adult cardiac valve surgery. Methods A total of 125 patients who underwent cardiac valve surgery in the first affiliated hospital of nanchang university between October 2016 and October 2018 were retrospectively reviewed. including age, gender, weight, height, pre-operative plasma creatinine, preoperative plasma NT-proBNP, number of valves involved, pre-operative EF and early postoperative outcomes. The independent pre-operative factors that have a significant impact on early post-operative outcomes after adult cardiac valve surgery were investigated. Prognostic value in early outcomes after adult cardiac valve surgery was analyzed by ROC curve analysis. Results preoperative plasma creatinine, preoperative plasma NT-proBNP and the number of valves involved in the complication group were significantly higher than that in non-complication group;BMI and pre-operative EF in the complication group was lower than that in the non-complication group ,with a statistically significant difference(PROC curve analysis was used to explore the predictive performance. Results in ROC curve analysis, the AUC for the preoperative plasma NT-proBNP was 0.806 (95% CI 0.712～0.900，PConclusion The elevated NT-proBNP and creatinine levels were independently correlated with the early post-operative outcomes, were two promising prognostic predictors for predicting the worse clinical outcomes . The pre-operative plasma NT-proBNP and the plasma creatinine combination was determined to help identify high-risk patients and make appropriate clinical decisions. |
