POLYOSTOTIC FIBROUS DYSPLASIA DIFFERENTIATED IN INTERMEDIATE-GRADE SPINDLE CELL SARCOMA: A CASE REPORT
| Autor: | Amanda Vanessa Lira dos Santos Lima, Joaquim Celestino da Silva Neto, Miquéias Oliveira de Lima Júnior, Cauê Fontan Soares, Riedel Frota, Arthur José Barbosa de França, Adilis Stepple Da Fonte Neto |
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| Rok vydání: | 2020 |
| Předmět: |
Nasal cavity
Pathology medicine.medical_specialty Periosteum medicine.diagnostic_test Maxillary sinus business.industry External carotid artery medicine.disease Pathology and Forensic Medicine medicine.anatomical_structure Frontal bone medicine.artery Biopsy medicine Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Surgery Spindle cell sarcoma Oral Surgery Polyostotic fibrous dysplasia business |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 130:e145 |
| ISSN: | 2212-4403 |
| DOI: | 10.1016/j.oooo.2020.04.170 |
| Popis: | A 53-year-old female patient presented with complaint of volume increase in the face with 5 months’ of evolution. Physical examination showed a right hemifacial tumor, spontaneous pain, dystopia, amaurosis, right nasal obstruction, and multinodular hardened lesions on the right upper alveolar ridge. The tomographic examination revealed hyperdense lesions in frontal bone enveloping the ethmoid bilaterally, maxillary sinus, and nasal cavity, in addition to the other long bones, which led to the diagnosis of polyostotic fibrous dysplasia. No other endocrinologic finding suggested a syndromic variant, and the rapid and progressive growth led the team to investigate the malignancy. After an angiotomographic study, intense periosteum activity and central vascularization by the external carotid artery were observed. Biopsy was chosen through the core biopsy method, in which the immunohistochemistry confirmed the differentiation in intermediate-grade spindle cell sarcoma. The proposed treatment was chemotherapy and radiotherapy, evolving to death within 3 months’ of the disease. |
| Databáze: | OpenAIRE |
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