Tracking the Emergence and Dissemination of a bla NDM-23 Gene in a Multidrug Resistance Plasmid of Klebsiella pneumoniae

Autor: Neris García-González, Beatriz Beamud, Begoña Fuster, Salvador Giner, Maria Victoria Domínguez, Antonia Sánchez, Jordi Sevilla, Teresa M. Coque, Concepción Gimeno, Fernando González-Candelas, Nuria Tormo, Carme Salvador, Victoria Domínguez, Javier Colomina, David Navarro, Llúcia Martínez, Antonio Burgos, Olalla Martínez, Barbara Gomila-Sard, Rosario Moreno, Inmaculada Vidal, Juan Carlos Rodriguez, Victoria Sánchez-Hellín
Rok vydání: 2023
Předmět:
Zdroj: Microbiology Spectrum. 11
ISSN: 2165-0497
DOI: 10.1128/spectrum.02585-22
Popis: At a time when antimicrobial resistance has become one of the biggest concerns worldwide, the emergence of novel alleles and extremely drug-resistant plasmids is a threat to public health worldwide, especially when they produce carbapenem resistance in one of the most problematic pathogens, such as Klebsiella pneumoniae . We used genomic epidemiology to describe the emergence of a novel NDM-23 allele and identify it in a MDR plasmid that has disseminated through a K. pneumoniae ST437 clone in several hospitals in Spain.
Databáze: OpenAIRE