Clinical and economic impact of recurrence in early-stage non-small-cell lung cancer following complete resection

Autor:	Howard West, Xiaohan Hu, Diana Chirovsky, Mark S Walker, Yuexi Wang, Alpana Kaushiva, Jon Tepsick, Ayman Samkari
Rok vydání:	2023
Předmět:	Cancer Research Oncology General Medicine
Zdroj:	Future Oncology.
ISSN:	1744-8301 1479-6694
Popis:	Aim: Real-world data on outcomes for early-stage non-small-cell lung cancer (NSCLC) are needed to better understand the benefits of new therapies. Methods: In this retrospective study using the ConcertAI Patient360™ database, overall survival and healthcare resource utilization were compared among patients with recurrent and non-recurrent completely resected stage IB-IIIA NSCLC. Results: Recurrence was associated with a shorter median overall survival compared with non-recurrence (31.5 months vs 75.6 months, respectively), lower survival probability 5-years post-resection, and higher healthcare resource utilization. Patients with late recurrence had a longer restricted mean survival time versus patients with early recurrence. Conclusion: Results from this real-world study highlight the potential value of preventing or delaying recurrence in patients with early-stage NSCLC.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::96aa4a08a488e05cbb59f8b9c801af6c https://doi.org/10.2217/fon-2023-0024 Zobrazit plný text záznamu