BODY FLUID VOLUMES AND PRESSOR RESPONSE TO ANGIOTENSIN II AND NOREPINEPHRINE IN PREGNANT RATS

Autor:	Akihiko Andoh
Rok vydání:	1983
Předmět:	Body fluid medicine.medical_specialty Isotope dilution method business.industry Body water Plasma renin activity Angiotensin II Norepinephrine (medication) Endocrinology Internal medicine Extracellular fluid Medicine Gestation business circulatory and respiratory physiology medicine.drug
Zdroj:	The KITAKANTO Medical Journal. 33:397-407
ISSN:	1883-6135 0023-1908
DOI:	10.2974/kmj1951.33.397
Popis:	The aims of the present study were to examine the appropriateness of the rat as a model for human pregnancy in distribution of body fluid volumes and pressor response to vasoconstrictor substances. Body fluid volumes and the pressor response to angiotensin II (AII) and norepinephrine (NE) were determined in unanesthetized nonpregnant and pregnant rats, at 6-10 days gestation (early gestation) and 16-20 days gestation (late gestation). The distribution of body fluid volumes was measured by an isotope dilution method; plasma volume (PV), extracellular fluid volume (ECFV), and total body water (TBW) by 131I-radio-iodinated serum albumin, 35S-sodium sulfate, and tritiated water respectively. Late gestation rats had signficantly (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::96a396585513fa0aebfde9f96df99c3b https://doi.org/10.2974/kmj1951.33.397 Zobrazit plný text záznamu