Hyperosmolar Solutions Effects on Cerebral Oxygenation and Metabolism

Autor:	Solodov Aa, A. A. Polupan, Petrikov Ss, U. V. Titova, Krylov Vv, H. T. Guseinova, L. T. Khamidova
Rok vydání:	2009
Předmět:	Intracerebral hemorrhage business.industry medicine.medical_treatment Metabolism Critical Care and Intensive Care Medicine Critical Care Nursing medicine.disease Oxygen tension Preload Cerebral oxygenation Anesthesia medicine Mannitol business Saline medicine.drug Intracranial pressure
Zdroj:	The Open Critical Care Medicine Journal. 2:18-27
ISSN:	1874-8287
Popis:	Purpose: To estimate the dynamics of cerebral oxygenation and metabolism during intracranial pressure (ICP) correction with 15% Mannitol and 7,2% saline in 6% HES 200/0,5. Methods: We analyzed 39 episodes of ICP correction with 15% Mannitol or 7,2% NaCl in 6% HES 200/0,5 ("Hyper- HAES") in 9 patients with intracranial hemorrhage (GCS 4-8). Monitoring of ICP, systemic hemodynamics, SvjO2 and cerebral microdialysis was used in all patients. Brain temperature (Tbr) and brain oxygen tension (PbrO2) were investi- gated in 5 patients. ICP > 20 mmHg was the indication for treatment. Results: The duration of ICP reduction below 20 mmHg was 121 ± 58 min for 15% Mannitol and 258 ± 122 min for "Hy- perHAES" (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::96918cc2ad453043c9222d24fc68ebec https://doi.org/10.2174/1874828700902010018 Zobrazit plný text záznamu