An improved and practical synthesis route to antiproliferative (±)-shikonin and its O-acyl derivatives

Autor:	Koji Higai, Mana Ono, Shoko Higashi, Shouki Abe, Ryota Saito, Setsuo Saito
Rok vydání:	2020
Předmět:	Olefin metathesis 010405 organic chemistry Chemistry Organic Chemistry Cancer cell 010402 general chemistry Highly selective Cytotoxicity 01 natural sciences Combinatorial chemistry 0104 chemical sciences
Zdroj:	Synthetic Communications. 51:738-746
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397911.2020.1853171
Popis:	Shikonin and its O-acyl derivatives are attracting increasing levels of attention among medicinal chemists due to their potencies as highly selective cytotoxic agents against cancer cells. However,...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::968eda3d117c58c21d98ebc5c5ef565c https://doi.org/10.1080/00397911.2020.1853171 Zobrazit plný text záznamu