Device Provides Sensitive Measures Of Cells' Metabolic Responses
| Autor: | R. M. Baum |
|---|---|
| Rok vydání: | 1989 |
| Předmět: | |
| Zdroj: | Chemical & Engineering News Archive. 67:20-22 |
| ISSN: | 2157-4936 0009-2347 |
| DOI: | 10.1021/cen-v067n044.p020 |
| Popis: | Science often is technique driven, especially if the new technique allows the routine measurement of a quantity that was difficult or impossible to measure previously. A device called a silicon microphysiometer may represent such a new technique. Developed by scientists at Molecular Devices Corp., Menlo Park, Calif., the device measures with high sensitivity in real time the metabolic responses of cells to physical and chemical stimuli. That capability opens up a wide range of research possibilities, some of which have been explored by J. Wallace Parce, John C. Owicki, and Karen M. Kercso, the Molecular Devices scientists primarily responsible for developing the microphysiometer. They find, for example, that the device can measure the metabolic responses of tumor cells to chemotherapeutic agents with enough sensitivity to distinguish between cells that are resistant and cells that are sensitive to a given drug; track the effect of virus infection on cells, as well as the efficacy of antiviral ... |
| Databáze: | OpenAIRE |
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