Ligand Adsorption and Exchange on Pegylated Gold Nanoparticles
| Autor: | Shengli Zou, Kumudu Siriwardana, Willard E. Collier, Erick S. Vasquez, Dongmao Zhang, Keisha B. Walters, Manuel Gadogbe, Siyam M. Ansar |
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| Rok vydání: | 2014 |
| Předmět: |
Molecular mass
Stereochemistry Chemistry Ligand Inorganic chemistry technology industry and agriculture Surfaces Coatings and Films Electronic Optical and Magnetic Materials Overlayer chemistry.chemical_compound General Energy Adsorption Dynamic light scattering Colloidal gold Physical and Theoretical Chemistry Saturation (chemistry) Ethylene glycol |
| Zdroj: | The Journal of Physical Chemistry C. 118:11111-11119 |
| ISSN: | 1932-7455 1932-7447 |
| DOI: | 10.1021/jp501391x |
| Popis: | Previous researchers proposed that thiolated poly(ethylene glycol) (PEG-SH) adopts a “mushroom-like” conformation on gold nanoparticles (AuNPs) in water. However, information regarding the size and permeability of the PEG-SH mushroom caps and surface area passivated by the PEG-SH mushroom stems are unavailable. Reported herein is our finding that AuNPs that are covered by saturation packed PEG-SHs all have large fractions of AuNP surface area available for ligand adsorption and exchange. The model ligands adenine and 2-mercaptobenzimidazole (2-MBI) can rapidly penetrate the PEG-SH overlayer and adsorb onto the AuNP surface. Most of the ligand adsorption and exchange occurs within the first minutes of the ligand addition. The fraction of AuNP surface area passivated by saturation packed model PEG-SHs are ∼25%, ∼20%, and ∼9% for PEG-SHs with molecular weights of 2000, 5000, and 30 000 g/mol, respectively. Localized surface plasmonic resonance and dynamic light scattering show that the PEG-SH overlayer is dr... |
| Databáze: | OpenAIRE |
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