Hyperplasia of the Gastric Mucosa Produced by Duodenal Obstruction

Autor:	R.D.E. Rumsey, G.P. Crean, D.F. Hogg
Rok vydání:	1969
Předmět:	medicine.medical_specialty Hepatology business.industry medicine.medical_treatment Peptic Stomach digestive oral and skin physiology Gastroenterology Distension Hyperplasia medicine.disease medicine.anatomical_structure Internal medicine Duodenum Gastric mucosa Medicine business Ligature Antrum
Zdroj:	Gastroenterology. 56:193-199
ISSN:	0016-5085
DOI:	10.1016/s0016-5085(69)80117-4
Popis:	A marked hyperplasia of the gastric mucosa was observed in rats after partial obstruction to the gastric outflow had been produced by tying a ligature around the duodenum. The effect was characterized by increases in the weight, surface area, and mucosal volume of the fundus and antrum, and there were proportional increases in the total parietal and total peptic cell populations. These effects were interpreted to mean that obstruction had caused an increase in the number of glands in the two parts of the stomach. The results suggest that the hyperplasia was due in some way to physical distension of the stomach since all of the other changes observed could be accounted for by the increase that occurred in surface area.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::965b4482bc83d892b41a514f5863a258 https://doi.org/10.1016/s0016-5085(69)80117-4 Zobrazit plný text záznamu