Usefulness of ventricular function values obtained using post-stress gated-SPECT in a diabetic population with clinical suspicion of ischaemic heart disease
| Autor: | S. Ruiz Solís, M. Maure Rico, B. Rodríguez Alfonso, C. Martínez Delgado, A.M. García Vicente, P. Talavera Rubio, M. Cortés Romera, A. Palomar Muñoz, A. Soriano Castrejón, V.M. Poblete García |
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| Rok vydání: | 2008 |
| Předmět: |
Microbiology (medical)
education.field_of_study medicine.medical_specialty Ejection fraction Heart disease business.industry Gated SPECT Immunology Population Diabetic angiopathy medicine.disease Internal medicine Diabetes mellitus medicine Cardiology Immunology and Allergy cardiovascular diseases education business Perfusion Pathological |
| Zdroj: | Revista Española de Medicina Nuclear (English Edition). 27:340-349 |
| ISSN: | 1578-200X |
| DOI: | 10.1016/s1578-200x(08)70041-x |
| Popis: | Objective To assess the clinical usefulness of left ventricular function values obtained using post-stress myocardial perfusion gated-SPECT in diabetic patients with suspected ischaemic heart disease (IHD). Materials and methods Sixty-one patients with diabetes mellitus (DM), with clinical suspicion of IHD and no previous history of heart disease were studied. Ergometric or pharmacological post-stress myocardial perfusion gated-SPECT was performed on all patients. The relationship between the ejection fraction values and ventricular volumes, and the perfusion study results, final diagnosis, severity of the perfusion defects and the clinical evolution was studied. The mean followup time was 14 months. Results All the ventricular function values independently showed significant differences between the groups with a normal and pathological perfusion study, and between groups with a final diagnosis of IHD and non-IHD. After multivariate logistic regression, the end-diastolic volume (EDV) was the only value which showed a statistical association with the pathological perfusion study, its severity and the final diagnosis of IHD. No statistical association was observed between the ventricular function values and the occurrence of cardiac events. Conclusions All the ventricular function values obtained by gated-SPECT added diagnostic information to the post-stress myocardial perfusion study in the diabetic population with suspected IHD; however, only EDV showed a statistical association with the pathological perfusion study, severity of defects and the final diagnosis of IHD. |
| Databáze: | OpenAIRE |
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