Esophageal Rhabdomyosarcoma
| Autor: | Yuri K Batoroev, Gia-Khanh Nguyen |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Pathology
medicine.medical_specialty Histology medicine.diagnostic_test Esophageal Rhabdomyosarcoma Esophageal disease business.industry General Medicine Esophageal cancer medicine.disease Pathology and Forensic Medicine medicine.anatomical_structure Biopsy medicine Sarcoma Esophagus Rhabdomyosarcoma business Esophageal Mass |
| Zdroj: | Acta Cytologica. 50:213-216 |
| ISSN: | 1938-2650 0001-5547 |
| Popis: | Background Primary esophageal rhabdomyosarcoma (PER) is a very rare neoplasm with only 15 cases reported in the literature. Of those, only 1 case underwent a preoperative cytologic evaluation. We report a case of PER with diagnosis by imprint cytology. Case A 55-year-old woman presented with dysphagia of 2 months' duration associated with fatigue and weight loss. Clinical and diagnostic imaging investigations revealed a large, submucosal mass lesion located in the lower part of the esophagus. A bite biopsy of the esophageal mass was performed under esophagoscopy. Two imprint smears were made from the biopsied tissue fragment and stained with the May-Grunwald-Giemsa method. The smears revealed abundant, pleomorphic, malignant cells with basophilic cytoplasm. Some spindle-shaped cancer cells showed intracytoplasmic cross-striations, indicating a pleomorphic rhabdomyosarcoma, as confirmed by histologic and immunohistochemical studies of the biopsied tumor tissue and resected tumor. Conclusion The presence of pleomorphic malignant cells with intracytoplasmic cross striations is a characteristic feature of pleomorphic rhabdomyosarcoma. |
| Databáze: | OpenAIRE |
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