Cardiovascular complications in patients with community-acquired pneumonia
| Autor: | Nicolò Vanoni, Francesco Blasi, Marta Di Pasquale, Sonia Henchi |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
business.industry General Medicine 030204 cardiovascular system & hematology medicine.disease Vaccination 03 medical and health sciences 0302 clinical medicine Atheroma 030228 respiratory system Community-acquired pneumonia Infectious disease (medical specialty) Heart failure Epidemiology medicine Myocardial infarction Endothelial dysfunction Intensive care medicine business |
| Zdroj: | Community Acquired Infection. 4:23 |
| ISSN: | 2225-6482 |
| Popis: | Community-acquired pneumonia (CAP) is the most frequent infectious disease, responsible for a great morbidity and mortality worldwide. It is known that poor outcome in CAP patients is not only directly related to pneumonia but also to comorbidities both during hospitalization and long term after discharge. Evidences show a high correlation between acute respiratory infections and increased risk of cardiovascular events (CVEs), such as acute myocardial infarction, arrhythmias, congestive heart failure, and stroke. The excessive systemic inflammatory response is responsible for hypoperfusion and activation of cytokines causing endothelial dysfunction, pro-coagulant effects, and atheroma instability. An established diagnostic tool to identify high-risk patients is not yet available, but cardiovascular biomarkers seem to be more effective than inflammatory molecules. Early identification of patients at higher risk for CVEs is mandatory to treat them effectively with prophylaxis medications, to establish adequate clinical surveillance and prevention with vaccinations. The present article reviews the epidemiology, pathophysiology, clinical presentation, risk factors, diagnosis, outcomes, and prevention of CVEs in patients hospitalized for CAP. |
| Databáze: | OpenAIRE |
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