Optimal Cerebral Perfusion Pressure in Head Injury
| Autor: | D. G. Changaris, R. A. Greenberg, C. P. McGraw |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Mean arterial pressure
Severe head injury business.industry musculoskeletal neural and ocular physiology Head injury Ischemia medicine.disease body regions nervous system Cerebral blood flow Anesthesia Hemorrhagic shock polycyclic compounds Medicine Cerebral perfusion pressure business psychological phenomena and processes |
| Zdroj: | Intracranial Pressure VII ISBN: 9783642739897 |
| DOI: | 10.1007/978-3-642-73987-3_166 |
| Popis: | The lowest Cerebral Perfusion Pressure (CPP) sustainable for days is unknown. An acute reduction in CPP below 45 alters sensorium (Stone et al. 1965, Williams 1968). Cerebral ischemia is reported to occur when CPP falls below 25–30 mmHg (Tyson and Jane 1982). It seems likely that the brain should be more sensitive to prolonged reductions in CPP. Previously published works by the authors show that all severely head injured patients who had a 48-hour CPP below 60 mm Hg died (of 136 patients with severe head injury, 24 fell into this category; Changaris et al. 1988). We sought to determine if early clinical improvement was more frequent when the 48-hr CPP was greater than 80 mmHg. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|