Life-Threatening Tumor Lysis Syndrome Within 12 Hours of a Single Dose of Corticosteroid in a Patient with Lymphoma
| Autor: | Grady Wick, Damiano Rondelli, Jose A.L. Arruda, April Brooks, Kalyani Perumal, Jerrold S. Levine |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Nephrology
medicine.medical_specialty Chemotherapy Pathology medicine.drug_class business.industry Laboratory monitoring medicine.medical_treatment Lymphoblastic lymphoma medicine.disease Gastroenterology Lymphoma Tumor lysis syndrome Internal medicine medicine Corticosteroid Significant risk business |
| Zdroj: | Kidney. 18:125-128 |
| ISSN: | 1865-5068 0940-7936 |
| DOI: | 10.1007/s00596-009-0090-5 |
| Popis: | Tumor lysis syndrome is an oncologic emergency characterized by electrolyte derangements and the frequent development of acute renal failure. We describe a patient with acute lymphoblastic lymphoma in whom rapid and severe tumor lysis syndrome developed within 10 h of the administration of a single dose of corticosteroid. Our case and a review of the literature indicate that patients with lymphoproliferative malignancies given a single dose of corticosteroid may be at significant risk for rapid and life-threatening tumor lysis syndrome. We recommend that such patients receive aggressive and frequent laboratory monitoring even in the setting of appropriate prophylaxis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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