Pathological anatomy of an experimental disease of small laboratory animals caused by encephalomyocarditis virus strain �MK-70

Autor: Dzhikidze Ek, Voskanian Na, Shevtsova Zv, Balaeva EIa, Krylova Ri
Rok vydání: 1977
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 84:1357-1361
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00805907
Popis: The results of a pathomorphological investigation of an experimental disease of small laboratory animals caused by strain EMK-70 of encephalomyocarditis virus isolated from monkeys are described. Regardless of the method of infection of the newborn and juvenile mice with the virus, they developed lesions of the brown fat, striated muscle, brain, and heart. The changes in guinea pigs were characterized by the development of severe myocarditis and encephalitis, accompanied by accumulation of virus antigen. The disease, caused by strain EMK-70 could not be differentiated from Coxsackie infection on the basis of the pathomorphological data. This fact must be taken into account when problems concerning the diagnosis of virus diseases at autopsy are examined.
Databáze: OpenAIRE