Autor: |
Michael J. Di Maso, Embarek Alwedi, Guy R. Humphrey, Richard Desmond, Louis-Charles Campeau, Lisa Jellett, John R. Naber, Hong Ren, Hsieh Yao D. Chang, Douglas A. L. Otte, Hong Gao, Michael A. Zompa, Si-Wei Zhang, Gary E. Martin, Alfred Y. Lee, Wenjun Liu, Francisco J. Guzman, Kevin M. Maloney, Feng Peng, Elizabeth Fisher, Rebecca T. Ruck, Dan Lehnherr, Anne E. Mohan, Glenn Spencer, Siqing Song, Kallol Basu, Rebecca A. Arvary, Sachin Lohani |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
Organic Process Research & Development. 24:2445-2452 |
ISSN: |
1520-586X 1083-6160 |
DOI: |
10.1021/acs.oprd.0c00248 |
Popis: |
A robust, green, and sustainable manufacturing process has been developed for the synthesis of gefapixant citrate, a P2X3 receptor antagonist that is under investigation for the treatment of refrac... |
Databáze: |
OpenAIRE |
Externí odkaz: |
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