| Autor: |
Xiaonan Shi, Jinghui Zhao, Yujie Huang, Dequan Jiao, Chen Chen, Bolin Zhu, Liying Liu, Wan Sun, Jie Ding |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Organic Chemistry Frontiers. 8:2250-2255 |
| ISSN: |
2052-4129 |
| Popis: |
We report efficient palladium-catalyzed domino Heck-silylation of alkene-tethered carbamoyl chlorides with hexamethyldisilane. By using this protocol, a variety of mono- and disilylated oxindoles were obtained in moderate to good yields. Notably, this research provides the first palladium-catalyzed methodology to synthesize diverse disilylated oxindoles at room temperature which is superior to previous methods. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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