Emerging Techniques in Imaging of Glioma Microenvironment
| Autor: | Seyed Ali Nabavizadeh, Ronald L. Wolf, Jeffrey B. Ware |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Tumor microenvironment
medicine.diagnostic_test business.industry medicine.medical_treatment food and beverages Magnetic resonance imaging medicine.disease 030218 nuclear medicine & medical imaging Resection Radiation therapy 03 medical and health sciences 0302 clinical medicine Glioma Medicine Radiology Nuclear Medicine and imaging business Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Topics in Magnetic Resonance Imaging. 29:103-114 |
| ISSN: | 1536-1004 0899-3459 |
| DOI: | 10.1097/rmr.0000000000000232 |
| Popis: | Magnetic resonance imaging (MRI) has been the cornerstone of imaging of brain tumors in the past 4 decades. Conventional MRI remains the workhorse for neuro-oncologic imaging, not only for basic information such as location, extent, and navigation but also able to provide information regarding proliferation and infiltration, angiogenesis, hemorrhage, and more. More sophisticated MRI sequences have extended the ability to assess and quantify these features; for example, permeability and perfusion acquisitions can assess blood-brain barrier disruption and angiogenesis, diffusion techniques can assess cellularity and infiltration, and spectroscopy can address metabolism. Techniques such as fMRI and diffusion fiber tracking can be helpful in diagnostic planning for resection and radiation therapy, and more sophisticated iterations of these techniques can extend our understanding of neurocognitive effects of these tumors and associated treatment responses and effects. More recently, MRI has been used to go beyond such morphological, physiological, and functional characteristics to assess the tumor microenvironment. The current review highlights multiple recent and emerging approaches in MRI to characterize the tumor microenvironment. |
| Databáze: | OpenAIRE |
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