MicroRNAs as Potential Biomarkers of Type 2 Diabetes Mellitus

Autor:	Andrey S. Glotov, A. A. Mikhailova, Yulia A. Nasykhova, Z. N. Tonyan
Rok vydání:	2021
Předmět:	Regulation of gene expression Potential biomarkers microRNA Genetics Type 2 Diabetes Mellitus Biology Bioinformatics Gene Human genetics
Zdroj:	Russian Journal of Genetics. 57:764-777
ISSN:	1608-3369 1022-7954
DOI:	10.1134/s1022795421060107
Popis:	MicroRNAs are small noncoding RNAs involved in post-transcriptional regulation of gene expression. In recent years, works demonstrating changes in the miRNA profile in tissues in type 2 diabetes mellitus were published. This work provides a systematic review of the results of 91 studies published from November 2009 to June 2020. Prospects for the use of miR-29a, -34a, -126, -144, -375 as potential biomarkers of type 2 diabetes mellitus are considered, and possible target genes of these miRNAs and mechanisms of the participation in glucose metabolism are also discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9557fa9021706d230fb478368737abe6 https://doi.org/10.1134/s1022795421060107 Zobrazit plný text záznamu Full text from SpringerLink